
Ready in: 20 minutes · Serves: 2 · Technique: Grilling · Storage: Airtight container in the fridge for up to 2 days.
Quick Answer
This Cheesy Pizza Panini combines classic pizza flavors in a crispy, toasted sandwich, perfect for cozy days.
There's something wonderfully cozy about making a delicious grilled sandwich, especially as we transition into the colder months of the year here in New York City. As the temperatures drop, I find myself longing for comforting dishes that evoke the warmth of home. And what could be more inviting than a Cheesy Pizza Panini? This delightful creation brings the classic flavors of pizza-melted cheese, savory sauce, and your choice of toppings-together in a crispy, toasted sandwich. It's perfect for Thanksgiving leftovers or holiday gatherings!
A Cozy Holiday Treat

Why You'll Love This Recipe
- Comforting, warm sandwich perfect for cold weather.
- Quick and easy to make, ideal for using up Thanksgiving leftovers.
- Melted cheese and savory sauce create an irresistible flavor combination.
- Customizable with your favorite pizza toppings.
- Can be enjoyed any time of the year for a satisfying meal.
Ingredients
Here's what you'll need to make this scrumptious Cheesy Pizza Panini:
Bread
- 2 slices of thick, rustic sourdough bread
Spread
- 1 tablespoon of butter, softened
Pizza Sauce
- ½ cup of pizza sauce
Cheese
- 4 oz of shredded mozzarella cheese
Toppings
- ¼ cup of shredded pepperoni or your choice of toppings (mushrooms, olives, or bell peppers work wonderfully)
Optional
- Fresh basil or oregano for an aromatic finish
How to Make Cheesy Pizza Panini (Step-by-Step)
Follow these simple steps to create a delicious Cheesy Pizza Panini that will warm your soul.
Step 1: Prep Your Ingredients
Begin by spreading a generous tablespoon of softened butter on one side of each slice of sourdough. The butter will create a beautifully golden crust.
Step 2: Assemble the Panini
On the unbuttered side of one slice, spread about ¼ cup of pizza sauce, then layer half of the shredded mozzarella cheese. Sprinkle your pepperoni or any toppings you've chosen, and finish with the remaining mozzarella. Place the second slice of bread on top, buttered side up.
Step 3: Heat the Pan
I prefer using a 10-inch cast-iron skillet, as it evenly distributes heat and lends a rustic charm to the panini. Heat your skillet over medium heat until it's hot enough that a drop of water dances across its surface.
Step 4: Grill to Perfection
Carefully place the assembled panini in the skillet. Cook for about 3-4 minutes, or until the bottom is golden and crispy. Use a spatula to flip it over gently and grill the other side, pressing down slightly with the spatula to ensure even browning.
Step 5: Check for Melting Goodness
After another 3-4 minutes, check to see if the mighty mozzarella has melted into a gooey delight. I usually look for just a hint of a jiggle in the center-not too stiff, not too oozy.
Step 6: Serve Up
Once it's perfectly grilled, remove the panini from the skillet and let it sit for a minute. This is key, as it allows the cheese to set slightly, making it easier to cut. Slice it in half and enjoy!

Common Mistakes to Avoid
- Skipping the butter on the bread; it's essential for achieving that irresistible crispy crust.
- Overstuffing the sandwich can lead to a soggy result; keep the toppings balanced.
- Cooking at too high a temperature can burn the bread before the cheese melts; medium heat is your friend.
Tips and Tricks for Success
- Experiment with different cheeses like provolone or fontina for a more complex flavor.
- Add a sprinkle of fresh herbs such as basil or oregano before serving to elevate the dish.
- Serve immediately while the cheese is still gooey and inviting for the best experience.
- Use a cast-iron skillet for even cooking and a deliciously crispy crust.
Variations
- Replace mozzarella with a blend of your favorite cheeses for added flavor.
- Substitute pepperoni with grilled vegetables, salami, or ham for a different twist.
- Try different types of bread, such as ciabatta or focaccia, for unique textures.
- Add spicy elements like jalapeños or banana peppers for a kick.
How to Serve
- Slice the panini in half diagonally for appealing presentation.
- Pair with a side salad or a bowl of soup for a hearty meal.
- Serve alongside marinara sauce for dipping to enhance the pizza flavors.
- Garnish with fresh basil or a drizzle of olive oil for an elegant touch.

Make Ahead and Storage
- Make Ahead: Assemble the panini and store it in the fridge for up to 1 day before grilling.
- Storage: Store any leftovers in an airtight container in the fridge for up to 2 days.
- Reheating: Reheat in an iron skillet or air fryer for a crispy exterior.
- Freezing: Not recommended, as the texture may suffer once thawed.
Recipe Notes / What I Learned
Through this testing, I realized how a simple sandwich can evoke nostalgia and warmth, especially when made with fresh ingredients. There's magic in the act of grilling, transforming humble ingredients into something extraordinary, perfect for fall gatherings.
Yield and Serving Size
Yield: 2 paninis · Serving Size: 1 panini
Nutrition Snapshot
Estimated Nutrition Per Serving: ~450 calories · 18g protein · 40g carbs · 25g fat

Recipe by:
Cheesy Pizza Panini for Cozy Days
Ingredients
Equipment
Method
- Begin by spreading a generous tablespoon of softened butter on one side of each slice of sourdough. The butter will create a beautifully golden crust.
- On the unbuttered side of one slice, spread about ¼ cup of pizza sauce, then layer half of the shredded mozzarella cheese. Sprinkle your pepperoni or any toppings you've chosen, and finish with the remaining mozzarella. Place the second slice of bread on top, buttered side up.
- Heat your skillet over medium heat until it's hot enough that a drop of water dances across its surface.
- Carefully place the assembled panini in the skillet. Cook for about 3-4 minutes, or until the bottom is golden and crispy. Use a spatula to flip it over gently and grill the other side, pressing down slightly with the spatula to ensure even browning.
- After another 3-4 minutes, check to see if the mighty mozzarella has melted into a gooey delight. Look for just a hint of a jiggle in the center—not too stiff, not too oozy.
- Once it’s perfectly grilled, remove the panini from the skillet and let it sit for a minute. This is key, as it allows the cheese to set slightly, making it easier to cut. Slice it in half and enjoy!
Notes
FAQs
1. Can I use any type of bread for this panini?
While thick, rustic sourdough is recommended for its flavor and texture, you can substitute with other types of bread such as ciabatta or whole grain for a different twist.
2. What toppings can I add to my Cheesy Pizza Panini?
Some great options include pepperoni, mushrooms, olives, bell peppers, or even cooked sausage. Feel free to get creative with your favorite pizza toppings!
3. How can I ensure the cheese melts perfectly?
Using low-moisture mozzarella helps achieve that gooey melt. Also, cooking over medium heat allows for even melting without burning the bread.
4. Can I make this panini ahead of time?
It's best enjoyed fresh, but you can assemble the ingredients in advance and cook right before serving. Leftovers can be stored in the fridge for up to 2 days.
5. What is the best way to reheat leftovers?
The best way to reheat a Cheesy Pizza Panini is in a skillet or air fryer to maintain its crispy exterior. Avoid using a microwave as it can make the bread soggy.




